Risk of Thromboembolism With Eltrombopag: A Case Report of Deep Vein Thrombosis and Bilateral Pulmonary Embolism

Eltrombopag is a second-line therapy for refractory thrombocytopenia from immune thrombocytopenic purpura (ITP). The medication is generally well tolerated but can lead to adverse thromboembolic complications in rare instances. We present a case of lower extremity deep vein thrombosis with bilateral...

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Detalles Bibliográficos
Autores principales: Ghumman, Ghulam Mujtaba, Fatima, Huda, Singh, Gunbir, Khalid, Taha, Ayoubi, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911261/
https://www.ncbi.nlm.nih.gov/pubmed/36788875
http://dx.doi.org/10.7759/cureus.33615
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author Ghumman, Ghulam Mujtaba
Fatima, Huda
Singh, Gunbir
Khalid, Taha
Ayoubi, Mohamed
author_facet Ghumman, Ghulam Mujtaba
Fatima, Huda
Singh, Gunbir
Khalid, Taha
Ayoubi, Mohamed
author_sort Ghumman, Ghulam Mujtaba
collection PubMed
description Eltrombopag is a second-line therapy for refractory thrombocytopenia from immune thrombocytopenic purpura (ITP). The medication is generally well tolerated but can lead to adverse thromboembolic complications in rare instances. We present a case of lower extremity deep vein thrombosis with bilateral pulmonary embolism in an ITP patient receiving eltrombopag. The patient underwent catheter-directed thrombolysis for pulmonary embolism. Eltrombopag was stopped on discharge, considering the potential cause of venous thrombosis.
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spelling pubmed-99112612023-02-13 Risk of Thromboembolism With Eltrombopag: A Case Report of Deep Vein Thrombosis and Bilateral Pulmonary Embolism Ghumman, Ghulam Mujtaba Fatima, Huda Singh, Gunbir Khalid, Taha Ayoubi, Mohamed Cureus Internal Medicine Eltrombopag is a second-line therapy for refractory thrombocytopenia from immune thrombocytopenic purpura (ITP). The medication is generally well tolerated but can lead to adverse thromboembolic complications in rare instances. We present a case of lower extremity deep vein thrombosis with bilateral pulmonary embolism in an ITP patient receiving eltrombopag. The patient underwent catheter-directed thrombolysis for pulmonary embolism. Eltrombopag was stopped on discharge, considering the potential cause of venous thrombosis. Cureus 2023-01-10 /pmc/articles/PMC9911261/ /pubmed/36788875 http://dx.doi.org/10.7759/cureus.33615 Text en Copyright © 2023, Ghumman et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Ghumman, Ghulam Mujtaba
Fatima, Huda
Singh, Gunbir
Khalid, Taha
Ayoubi, Mohamed
Risk of Thromboembolism With Eltrombopag: A Case Report of Deep Vein Thrombosis and Bilateral Pulmonary Embolism
title Risk of Thromboembolism With Eltrombopag: A Case Report of Deep Vein Thrombosis and Bilateral Pulmonary Embolism
title_full Risk of Thromboembolism With Eltrombopag: A Case Report of Deep Vein Thrombosis and Bilateral Pulmonary Embolism
title_fullStr Risk of Thromboembolism With Eltrombopag: A Case Report of Deep Vein Thrombosis and Bilateral Pulmonary Embolism
title_full_unstemmed Risk of Thromboembolism With Eltrombopag: A Case Report of Deep Vein Thrombosis and Bilateral Pulmonary Embolism
title_short Risk of Thromboembolism With Eltrombopag: A Case Report of Deep Vein Thrombosis and Bilateral Pulmonary Embolism
title_sort risk of thromboembolism with eltrombopag: a case report of deep vein thrombosis and bilateral pulmonary embolism
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911261/
https://www.ncbi.nlm.nih.gov/pubmed/36788875
http://dx.doi.org/10.7759/cureus.33615
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