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Neprilysin Inhibitors in Heart Failure: The Science, Mechanism of Action, Clinical Studies, and Unanswered Questions

This article provides a contemporary review and a new perspective on the role of neprilysin inhibition in heart failure (HF) in the context of recent clinical trials and addresses potential mechanisms and unanswered questions in certain HF patient populations. Neprilysin is an endopeptidase that cle...

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Detalles Bibliográficos
Autores principales: Bozkurt, Biykem, Nair, Ajith P., Misra, Arunima, Scott, Claire Z., Mahar, Jamal H., Fedson, Savitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911324/
https://www.ncbi.nlm.nih.gov/pubmed/36777165
http://dx.doi.org/10.1016/j.jacbts.2022.05.010