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Spatial Distribution of Calcium Sparks Determines Their Ability to Induce Afterdepolarizations in Human Atrial Myocytes

Analysis of the spatio-temporal distribution of calcium sparks showed a preferential increase in sparks near the sarcolemma in atrial myocytes from patients with atrial fibrillation (AF), linked to higher ryanodine receptor (RyR2) phosphorylation at s2808 and lower calsequestrin-2 levels. Mathematic...

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Detalles Bibliográficos
Autores principales:	Tarifa, Carmen, Vallmitjana, Alexander, Jiménez-Sábado, Verónica, Marchena, Miquel, Llach, Anna, Herraiz-Martínez, Adela, Godoy-Marín, Héctor, Nolla-Colomer, Carme, Ginel, Antonino, Viñolas, Xavier, Montiel, José, Ciruela, Francisco, Echebarria, Blas, Benítez, Raúl, Cinca, Juan, Hove-Madsen, Leif
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Research - Clinical
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911326/ https://www.ncbi.nlm.nih.gov/pubmed/36777175 http://dx.doi.org/10.1016/j.jacbts.2022.07.013

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