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ZBTB12 is a molecular barrier to dedifferentiation in human pluripotent stem cells

Development is generally viewed as one-way traffic of cell state transition from primitive to developmentally advanced states. However, molecular mechanisms that ensure the unidirectional transition of cell fates remain largely unknown. Through exact transcription start site mapping, we report an ev...

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Detalles Bibliográficos
Autores principales: Han, Dasol, Liu, Guojing, Oh, Yujeong, Oh, Seyoun, Yang, Seungbok, Mandjikian, Lori, Rani, Neha, Almeida, Maria C., Kosik, Kenneth S., Jang, Jiwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911396/
https://www.ncbi.nlm.nih.gov/pubmed/36759523
http://dx.doi.org/10.1038/s41467-023-36178-9