Two distinct binding modes provide the RNA-binding protein RbFox with extraordinary sequence specificity

Specificity of RNA-binding proteins for target sequences varies considerably. Yet, it is not understood how certain few proteins achieve markedly higher sequence specificity than most others. Here we show that the RNA Recognition Motif of RbFox accomplishes extraordinary sequence specificity by empl...

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Detalles Bibliográficos
Autores principales: Ye, Xuan, Yang, Wen, Yi, Soon, Zhao, Yanan, Varani, Gabriele, Jankowsky, Eckhard, Yang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911399/
https://www.ncbi.nlm.nih.gov/pubmed/36759600
http://dx.doi.org/10.1038/s41467-023-36394-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911399/
https://www.ncbi.nlm.nih.gov/pubmed/36759600
http://dx.doi.org/10.1038/s41467-023-36394-3

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