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Two distinct binding modes provide the RNA-binding protein RbFox with extraordinary sequence specificity
Specificity of RNA-binding proteins for target sequences varies considerably. Yet, it is not understood how certain few proteins achieve markedly higher sequence specificity than most others. Here we show that the RNA Recognition Motif of RbFox accomplishes extraordinary sequence specificity by empl...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911399/ https://www.ncbi.nlm.nih.gov/pubmed/36759600 http://dx.doi.org/10.1038/s41467-023-36394-3 |