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The COVID-19, tuberculosis and HIV/AIDS: Ménage à Trois

In December 2019, a novel pneumonic condition, Coronavirus disease 2019 (COVID- 19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), broke out in China and spread globally. The presentation of COVID-19 is more severe in persons with underlying medical conditions such as Tuberc...

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Autores principales: Udoakang, Aniefiok John, Djomkam Zune, Alexandra Lindsey, Tapela, Kesego, Nganyewo, Nora Nghochuzie, Olisaka, Frances Ngozi, Anyigba, Claudia Adzo, Tawiah-Eshun, Sylvia, Owusu, Irene Amoakoh, Paemka, Lily, Awandare, Gordon A., Quashie, Peter Kojo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911459/
https://www.ncbi.nlm.nih.gov/pubmed/36776887
http://dx.doi.org/10.3389/fimmu.2023.1104828
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author Udoakang, Aniefiok John
Djomkam Zune, Alexandra Lindsey
Tapela, Kesego
Nganyewo, Nora Nghochuzie
Olisaka, Frances Ngozi
Anyigba, Claudia Adzo
Tawiah-Eshun, Sylvia
Owusu, Irene Amoakoh
Paemka, Lily
Awandare, Gordon A.
Quashie, Peter Kojo
author_facet Udoakang, Aniefiok John
Djomkam Zune, Alexandra Lindsey
Tapela, Kesego
Nganyewo, Nora Nghochuzie
Olisaka, Frances Ngozi
Anyigba, Claudia Adzo
Tawiah-Eshun, Sylvia
Owusu, Irene Amoakoh
Paemka, Lily
Awandare, Gordon A.
Quashie, Peter Kojo
author_sort Udoakang, Aniefiok John
collection PubMed
description In December 2019, a novel pneumonic condition, Coronavirus disease 2019 (COVID- 19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), broke out in China and spread globally. The presentation of COVID-19 is more severe in persons with underlying medical conditions such as Tuberculosis (TB), Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) and other pneumonic conditions. All three diseases are of global concern and can significantly affect the lungs with characteristic cytokine storm, immunosuppression, and respiratory failure. Co-infections of SARS-CoV-2 with HIV and Mycobacterium tuberculosis (Mtb) have been reported, which may influence their pathogenesis and disease progression. Pulmonary TB and HIV/AIDS patients could be more susceptible to SARS-CoV-2 infection leading to lethal synergy and disease severity. Therefore, the biological and epidemiological interactions of COVID-19, HIV/AIDS, and TB need to be understood holistically. While data is needed to predict the impact of the COVID-19 pandemic on these existing diseases, it is necessary to review the implications of the evolving COVID-19 management on HIV/AIDS and TB control, including therapy and funding. Also, the impact of long COVID on patients, who may have this co-infection. Thus, this review highlights the implications of COVID-19, HIV/AIDS, and TB co-infection compares disease mechanisms, addresses growing concerns, and suggests a direction for improved diagnosis and general management.
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spelling pubmed-99114592023-02-11 The COVID-19, tuberculosis and HIV/AIDS: Ménage à Trois Udoakang, Aniefiok John Djomkam Zune, Alexandra Lindsey Tapela, Kesego Nganyewo, Nora Nghochuzie Olisaka, Frances Ngozi Anyigba, Claudia Adzo Tawiah-Eshun, Sylvia Owusu, Irene Amoakoh Paemka, Lily Awandare, Gordon A. Quashie, Peter Kojo Front Immunol Immunology In December 2019, a novel pneumonic condition, Coronavirus disease 2019 (COVID- 19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), broke out in China and spread globally. The presentation of COVID-19 is more severe in persons with underlying medical conditions such as Tuberculosis (TB), Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) and other pneumonic conditions. All three diseases are of global concern and can significantly affect the lungs with characteristic cytokine storm, immunosuppression, and respiratory failure. Co-infections of SARS-CoV-2 with HIV and Mycobacterium tuberculosis (Mtb) have been reported, which may influence their pathogenesis and disease progression. Pulmonary TB and HIV/AIDS patients could be more susceptible to SARS-CoV-2 infection leading to lethal synergy and disease severity. Therefore, the biological and epidemiological interactions of COVID-19, HIV/AIDS, and TB need to be understood holistically. While data is needed to predict the impact of the COVID-19 pandemic on these existing diseases, it is necessary to review the implications of the evolving COVID-19 management on HIV/AIDS and TB control, including therapy and funding. Also, the impact of long COVID on patients, who may have this co-infection. Thus, this review highlights the implications of COVID-19, HIV/AIDS, and TB co-infection compares disease mechanisms, addresses growing concerns, and suggests a direction for improved diagnosis and general management. Frontiers Media S.A. 2023-01-27 /pmc/articles/PMC9911459/ /pubmed/36776887 http://dx.doi.org/10.3389/fimmu.2023.1104828 Text en Copyright © 2023 Udoakang, Djomkam Zune, Tapela, Nganyewo, Olisaka, Anyigba, Tawiah-Eshun, Owusu, Paemka, Awandare and Quashie https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Udoakang, Aniefiok John
Djomkam Zune, Alexandra Lindsey
Tapela, Kesego
Nganyewo, Nora Nghochuzie
Olisaka, Frances Ngozi
Anyigba, Claudia Adzo
Tawiah-Eshun, Sylvia
Owusu, Irene Amoakoh
Paemka, Lily
Awandare, Gordon A.
Quashie, Peter Kojo
The COVID-19, tuberculosis and HIV/AIDS: Ménage à Trois
title The COVID-19, tuberculosis and HIV/AIDS: Ménage à Trois
title_full The COVID-19, tuberculosis and HIV/AIDS: Ménage à Trois
title_fullStr The COVID-19, tuberculosis and HIV/AIDS: Ménage à Trois
title_full_unstemmed The COVID-19, tuberculosis and HIV/AIDS: Ménage à Trois
title_short The COVID-19, tuberculosis and HIV/AIDS: Ménage à Trois
title_sort covid-19, tuberculosis and hiv/aids: ménage à trois
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911459/
https://www.ncbi.nlm.nih.gov/pubmed/36776887
http://dx.doi.org/10.3389/fimmu.2023.1104828
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