Unique DUOX2(+)ACE2(+) small cholangiocytes are pathogenic targets for primary biliary cholangitis

Cholangiocytes play a crucial role in bile formation. Cholangiocyte injury causes cholestasis, including primary biliary cholangitis (PBC). However, the etiology of PBC remains unclear despite being characterized as an autoimmune disease. Using single-cell RNA sequencing (scRNA-seq), fluorescence-ac...

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Detalles Bibliográficos
Autores principales: Li, Xi, Li, Yan, Xiao, Jintao, Wang, Huiwen, Guo, Yan, Mao, Xiuru, Shi, Pan, Hou, Yanliang, Zhang, Xiaoxun, Zhao, Nan, Zheng, Minghua, He, Yonghong, Ding, Jingjing, Tan, Ya, Liao, Min, Li, Ling, Peng, Ying, Li, Xuan, Pan, Qiong, Xie, Qiaoling, Li, Qiao, Li, Jianwei, Li, Ying, Chen, Zhe, Huang, Yongxiu, Assis, David N., Cai, Shi-Ying, Boyer, James L., Huang, Xuequan, Tang, Can-E, Liu, Xiaowei, Peng, Shifang, Chai, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911648/
https://www.ncbi.nlm.nih.gov/pubmed/36759512
http://dx.doi.org/10.1038/s41467-022-34606-w

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