Single-cell RNA sequencing identifies Fgf23-expressing osteocytes in response to 1,25-dihydroxyvitamin D(3) treatment

Fibroblast growth factor 23 (FGF23), a hormone, mainly produced by osteocytes, regulates phosphate and vitamin D metabolism. By contrast, 1,25-dihydroxyvitamin D(3), the active form of vitamin D, has been shown to enhance FGF23 production. While it is likely that osteocytes are heterogenous in terms...

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Detalles Bibliográficos
Autores principales: Hanai, Ayako, Kawabata, Ayako, Nakajima, Kenta, Masuda, Kazuhiro, Urakawa, Itaru, Abe, Masahiro, Yamazaki, Yuji, Fukumoto, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911654/
https://www.ncbi.nlm.nih.gov/pubmed/36776964
http://dx.doi.org/10.3389/fphys.2023.1102751

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