Cargando…

Review: Improving quality of life in patients with differentiated thyroid cancer

Well differentiated thyroid cancer is a common malignancy diagnosed in young patients. The prognosis tends to be excellent, so years of survivorship is expected with low risk disease. When making treatment decisions, physicians should consider long-term quality of life outcomes when guiding patients...

Descripción completa

Detalles Bibliográficos
Autores principales: Pace-Asciak, Pia, Russell, Jonathon O., Tufano, Ralph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911681/
https://www.ncbi.nlm.nih.gov/pubmed/36776310
http://dx.doi.org/10.3389/fonc.2023.1032581
_version_ 1784885040626270208
author Pace-Asciak, Pia
Russell, Jonathon O.
Tufano, Ralph P.
author_facet Pace-Asciak, Pia
Russell, Jonathon O.
Tufano, Ralph P.
author_sort Pace-Asciak, Pia
collection PubMed
description Well differentiated thyroid cancer is a common malignancy diagnosed in young patients. The prognosis tends to be excellent, so years of survivorship is expected with low risk disease. When making treatment decisions, physicians should consider long-term quality of life outcomes when guiding patients. The implications for treating indolent, slow growing tumors are immense and warrant careful consideration for the functioning years ahead. Surgery is the standard of care for most patients, however for a subset of patients, active surveillance is appropriate. For those wishing to treat their cancer in a more active way, novel remote access approaches have emerged to avoid a cervical incision. In the era of “doing less”, options have further expanded to include minimally invasive approaches, such as radiofrequency ablation that avoids an incision, time off work, a general anesthetic, and the possibility of post-treatment hypothyroidism. In this narrative review, we examine the health related quality of life effects that surgery has on patients with thyroid cancer, including some of the newer innovations that have been developed to address patient concerns. We also review the impact that less aggressive treatment has on patient care and overall wellbeing in terms of active surveillance, reduced doses of radioactive iodine (RAI) treatment, or minimally invasive techniques such as radiofrequency ablation (RFA) for low risk thyroid disease.
format Online
Article
Text
id pubmed-9911681
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-99116812023-02-11 Review: Improving quality of life in patients with differentiated thyroid cancer Pace-Asciak, Pia Russell, Jonathon O. Tufano, Ralph P. Front Oncol Oncology Well differentiated thyroid cancer is a common malignancy diagnosed in young patients. The prognosis tends to be excellent, so years of survivorship is expected with low risk disease. When making treatment decisions, physicians should consider long-term quality of life outcomes when guiding patients. The implications for treating indolent, slow growing tumors are immense and warrant careful consideration for the functioning years ahead. Surgery is the standard of care for most patients, however for a subset of patients, active surveillance is appropriate. For those wishing to treat their cancer in a more active way, novel remote access approaches have emerged to avoid a cervical incision. In the era of “doing less”, options have further expanded to include minimally invasive approaches, such as radiofrequency ablation that avoids an incision, time off work, a general anesthetic, and the possibility of post-treatment hypothyroidism. In this narrative review, we examine the health related quality of life effects that surgery has on patients with thyroid cancer, including some of the newer innovations that have been developed to address patient concerns. We also review the impact that less aggressive treatment has on patient care and overall wellbeing in terms of active surveillance, reduced doses of radioactive iodine (RAI) treatment, or minimally invasive techniques such as radiofrequency ablation (RFA) for low risk thyroid disease. Frontiers Media S.A. 2023-01-27 /pmc/articles/PMC9911681/ /pubmed/36776310 http://dx.doi.org/10.3389/fonc.2023.1032581 Text en Copyright © 2023 Pace-Asciak, Russell and Tufano https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Pace-Asciak, Pia
Russell, Jonathon O.
Tufano, Ralph P.
Review: Improving quality of life in patients with differentiated thyroid cancer
title Review: Improving quality of life in patients with differentiated thyroid cancer
title_full Review: Improving quality of life in patients with differentiated thyroid cancer
title_fullStr Review: Improving quality of life in patients with differentiated thyroid cancer
title_full_unstemmed Review: Improving quality of life in patients with differentiated thyroid cancer
title_short Review: Improving quality of life in patients with differentiated thyroid cancer
title_sort review: improving quality of life in patients with differentiated thyroid cancer
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911681/
https://www.ncbi.nlm.nih.gov/pubmed/36776310
http://dx.doi.org/10.3389/fonc.2023.1032581
work_keys_str_mv AT paceasciakpia reviewimprovingqualityoflifeinpatientswithdifferentiatedthyroidcancer
AT russelljonathono reviewimprovingqualityoflifeinpatientswithdifferentiatedthyroidcancer
AT tufanoralphp reviewimprovingqualityoflifeinpatientswithdifferentiatedthyroidcancer