Suppression of microRNA-222-3p ameliorates ulcerative colitis and colitis-associated colorectal cancer to protect against oxidative stress via targeting BRG1 to activate Nrf2/HO-1 signaling pathway

Oxidative stress is an important pathogenic factor in ulcerative colitis (UC) and colitis-associated colorectal cancer (CAC), further impairing the entire colon. Intestinal epithelial cells (IECs) are crucial components of innate immunity and play an important role in maintaining intestinal barrier...

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Detalles Bibliográficos
Autores principales: Wang, Xue-jun, Zhang, Dan, Yang, Yan-ting, Li, Xiao-ying, Li, Hong-na, Zhang, Xiao-peng, Long, Jun-yi, Lu, Yun-qiong, Liu, Li, Yang, Guang, Liu, Jie, Hong, Jue, Wu, Huan-gan, Ma, Xiao-peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911687/
https://www.ncbi.nlm.nih.gov/pubmed/36776858
http://dx.doi.org/10.3389/fimmu.2023.1089809

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