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Visualizing RNA conformational and architectural heterogeneity in solution

RNA flexibility is reflected in its heterogeneous conformation. Through direct visualization using atomic force microscopy (AFM) and the adenosylcobalamin riboswitch aptamer domain as an example, we show that a single RNA sequence folds into conformationally and architecturally heterogeneous structu...

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Detalles Bibliográficos
Autores principales:	Ding, Jienyu, Lee, Yun-Tzai, Bhandari, Yuba, Schwieters, Charles D., Fan, Lixin, Yu, Ping, Tarosov, Sergey G., Stagno, Jason R., Ma, Buyong, Nussinov, Ruth, Rein, Alan, Zhang, Jinwei, Wang, Yun-Xing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911696/ https://www.ncbi.nlm.nih.gov/pubmed/36759615 http://dx.doi.org/10.1038/s41467-023-36184-x

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