Angiotensin-converting enzyme inhibitor promotes angiogenesis through Sp1/Sp3-mediated inhibition of notch signaling in male mice

Angiogenesis is a critical pathophysiological process involved in organ growth and various diseases. Transcription factors Sp1/Sp3 are necessary for fetal development and tumor growth. Sp1/Sp3 proteins were downregulated in the capillaries of the gastrocnemius in patients with critical limb ischemia...

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Detalles Bibliográficos
Autores principales: Lu, Hanlin, Yuan, Peidong, Ma, Xiaoping, Jiang, Xiuxin, Liu, Shaozhuang, Ma, Chang, Philipsen, Sjaak, Zhang, Qunye, Yang, Jianmin, Xu, Feng, Zhang, Cheng, Zhang, Yun, Zhang, Wencheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911748/
https://www.ncbi.nlm.nih.gov/pubmed/36759621
http://dx.doi.org/10.1038/s41467-023-36409-z

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