Sec61 blockade therapy overrides resistance to proteasome inhibitors and immunomodulatory drugs in multiple myeloma

Multiple Myeloma (MM) is an incurable neoplasm of mature B cells and the second most prevalent hematological malignancy worldwide. While combinations of proteasome inhibitors like bortezomib (Bz) and immunomodulators (IMiDs) like lenalinomide (Len) are generally effective in newly diagnosed patients...

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Detalles Bibliográficos
Autores principales: Domenger, Antoine, Ricci, Daniela, Mayau, Véronique, Majlessi, Laleh, Marcireau, Christophe, Dadaglio, Gilles, Demangel, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911829/
https://www.ncbi.nlm.nih.gov/pubmed/36776330
http://dx.doi.org/10.3389/fonc.2023.1110916

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