Cancer, diabetes, survival and glycemic control: a large multisite analysis

AIM: To determine overall survival (OS) and glycemic control in patients with cancer and diabetes. MATERIALS & METHODS: Patients of our institution with breast, colon, lung, pancreas and prostate cancer were retrospectively reviewed. OS was compared between matched patients with and without diab...

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Detalles Bibliográficos
Autores principales: Karlin, Nina J, Kosiorek, Heidi E, Verona, Patricia M, Coppola, Kyle E, Cook, Curtiss B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912249/
https://www.ncbi.nlm.nih.gov/pubmed/36788982
http://dx.doi.org/10.2144/fsoa-2022-0018
Descripción
Sumario:AIM: To determine overall survival (OS) and glycemic control in patients with cancer and diabetes. MATERIALS & METHODS: Patients of our institution with breast, colon, lung, pancreas and prostate cancer were retrospectively reviewed. OS was compared between matched patients with and without diabetes, and changes in glucose value over time were assessed. RESULTS: For 3934 patients each with and without diabetes, adjusted analysis showed no difference in OS according to diabetes status (hazard ratio: 1.07; 95% CI: 0.96–1.20). Mean glucose values decreased over time in patients with and without diabetes (p = 0.01). CONCLUSION: In this large study of patients with five common cancers, the co-occurrence of diabetes did not affect OS. Cancer did not adversely affect glucose levels.

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