A recombinant Der p 1-specific allergen-toxin demonstrates superior killing of allergen-reactive IgG(+) hybridomas in comparison to its recombinant allergen-drug conjugate

INTRODUCTION: Current treatments for asthma help to alleviate clinical symptoms but do not cure the disease. In this study, we explored a novel therapeutic approach for the treatment of house dust mite allergen Der p 1induced asthma by aiming to eliminate specific population of B-cells involved in m...

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Detalles Bibliográficos
Autores principales: Daramola, A K, Akinrinmade, O A, Fajemisin, E A, Naran, K, Mthembu, N, Hadebe, S, Brombacher, F, Huysamen, A M, Fadeyi, O E, Hunter, R, Barth, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Immunotherapy of Asthma and Allergy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912260/
https://www.ncbi.nlm.nih.gov/pubmed/36789295
http://dx.doi.org/10.1093/immadv/ltac023

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