Neurotransmitter transporter occupancy following administration of centanafadine sustained-release tablets: A phase 1 study in healthy male adults

BACKGROUND: Centanafadine is an inhibitor of reuptake transporters for norepinephrine (NET), dopamine (DAT) and serotonin (SERT). AIMS: This phase 1, adaptive-design positron emission tomography study investigated the occupancy time course of NET, DAT, and SERT and the relationship to centanafadine...

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Detalles Bibliográficos
Autores principales: Matuskey, David, Gallezot, Jean-Dominique, Nabulsi, Nabeel, Henry, Shannan, Torres, Kristen, Dias, Mark, Angarita, Gustavo A, Huang, Yiyun, Shoaf, Susan E, Carson, Richard E, Mehrotra, Shailly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912308/
https://www.ncbi.nlm.nih.gov/pubmed/36515395
http://dx.doi.org/10.1177/02698811221140008

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