The Transcriptional Response to Lung-Targeting Lipid Nanoparticles in Vivo

[Image: see text] Lipid nanoparticles (LNPs) have delivered RNA to hepatocytes in patients, underscoring the potential impact of nonliver delivery. Scientists can shift LNP tropism to the lung by adding cationic helper lipids; however, the biological response to these LNPs remains understudied. To e...

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Detalles Bibliográficos
Autores principales: Radmand, Afsane, Lokugamage, Melissa P., Kim, Hyejin, Dobrowolski, Curtis, Zenhausern, Ryan, Loughrey, David, Huayamares, Sebastian G., Hatit, Marine Z. C., Ni, Huanzhen, Del Cid, Ada, Da Silva Sanchez, Alejandro J., Paunovska, Kalina, Schrader Echeverri, Elisa, Shajii, Aram, Peck, Hannah, Santangelo, Philip J., Dahlman, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912332/
https://www.ncbi.nlm.nih.gov/pubmed/36701517
http://dx.doi.org/10.1021/acs.nanolett.2c04479

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