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Preparation of chitosan nanoparticle containing recombinant CD44v antigen and evaluation of its immunization capacity against breast cancer in BALB/c mice

OBJECTIVE(S): Breast tumors show heterogeneity containing cancer stem cells as a small subpopulation of a tumor mass. CD44 as a cancer stem cells antigen is abnormally expressed by carcinomas of epithelial origin. Also, overexpression of CD44 variable isoforms (CD44v) is associated with malignancy i...

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Detalles Bibliográficos
Autores principales: Gheybi, Elaheh, Asoodeh, Ahmad, Amani, Jafar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912563/
https://www.ncbi.nlm.nih.gov/pubmed/36759786
http://dx.doi.org/10.1186/s12885-023-10614-x

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