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Bacteroidetes to Firmicutes: captivity changes the gut microbiota composition and diversity in a social subterranean rodent

BACKGROUND: In mammals, the gut microbiota has important effects on the health of their hosts. Recent research highlights that animal populations that live in captivity often differ in microbiota diversity and composition from wild populations. However, the changes that may occur when animals move t...

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Autores principales: Bensch, Hanna M., Tolf, Conny, Waldenström, Jonas, Lundin, Daniel, Zöttl, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912604/
https://www.ncbi.nlm.nih.gov/pubmed/36765400
http://dx.doi.org/10.1186/s42523-023-00231-1
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author Bensch, Hanna M.
Tolf, Conny
Waldenström, Jonas
Lundin, Daniel
Zöttl, Markus
author_facet Bensch, Hanna M.
Tolf, Conny
Waldenström, Jonas
Lundin, Daniel
Zöttl, Markus
author_sort Bensch, Hanna M.
collection PubMed
description BACKGROUND: In mammals, the gut microbiota has important effects on the health of their hosts. Recent research highlights that animal populations that live in captivity often differ in microbiota diversity and composition from wild populations. However, the changes that may occur when animals move to captivity remain difficult to predict and factors generating such differences are poorly understood. Here we compare the bacterial gut microbiota of wild and captive Damaraland mole-rats (Fukomys damarensis) originating from a population in the southern Kalahari Desert to characterise the changes of the gut microbiota that occur from one generation to the next generation in a long-lived, social rodent species. RESULTS: We found a clear divergence in the composition of the gut microbiota of captive and wild Damaraland mole-rats. Although the dominating higher-rank bacterial taxa were the same in the two groups, captive animals had an increased ratio of relative abundance of Firmicutes to Bacteroidetes compared to wild animals. The Amplicon Sequence Variants (ASVs) that were strongly associated with wild animals were commonly members of the same bacterial families as those strongly associated with captive animals. Captive animals had much higher ASV richness compared to wild-caught animals, explained by an increased richness within the Firmicutes. CONCLUSION: We found that the gut microbiota of captive hosts differs substantially from the gut microbiota composition of wild hosts. The largest differences between the two groups were found in shifts in relative abundances and diversity of Firmicutes and Bacteroidetes. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s42523-023-00231-1.
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spelling pubmed-99126042023-02-11 Bacteroidetes to Firmicutes: captivity changes the gut microbiota composition and diversity in a social subterranean rodent Bensch, Hanna M. Tolf, Conny Waldenström, Jonas Lundin, Daniel Zöttl, Markus Anim Microbiome Research BACKGROUND: In mammals, the gut microbiota has important effects on the health of their hosts. Recent research highlights that animal populations that live in captivity often differ in microbiota diversity and composition from wild populations. However, the changes that may occur when animals move to captivity remain difficult to predict and factors generating such differences are poorly understood. Here we compare the bacterial gut microbiota of wild and captive Damaraland mole-rats (Fukomys damarensis) originating from a population in the southern Kalahari Desert to characterise the changes of the gut microbiota that occur from one generation to the next generation in a long-lived, social rodent species. RESULTS: We found a clear divergence in the composition of the gut microbiota of captive and wild Damaraland mole-rats. Although the dominating higher-rank bacterial taxa were the same in the two groups, captive animals had an increased ratio of relative abundance of Firmicutes to Bacteroidetes compared to wild animals. The Amplicon Sequence Variants (ASVs) that were strongly associated with wild animals were commonly members of the same bacterial families as those strongly associated with captive animals. Captive animals had much higher ASV richness compared to wild-caught animals, explained by an increased richness within the Firmicutes. CONCLUSION: We found that the gut microbiota of captive hosts differs substantially from the gut microbiota composition of wild hosts. The largest differences between the two groups were found in shifts in relative abundances and diversity of Firmicutes and Bacteroidetes. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s42523-023-00231-1. BioMed Central 2023-02-10 /pmc/articles/PMC9912604/ /pubmed/36765400 http://dx.doi.org/10.1186/s42523-023-00231-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research
Bensch, Hanna M.
Tolf, Conny
Waldenström, Jonas
Lundin, Daniel
Zöttl, Markus
Bacteroidetes to Firmicutes: captivity changes the gut microbiota composition and diversity in a social subterranean rodent
title Bacteroidetes to Firmicutes: captivity changes the gut microbiota composition and diversity in a social subterranean rodent
title_full Bacteroidetes to Firmicutes: captivity changes the gut microbiota composition and diversity in a social subterranean rodent
title_fullStr Bacteroidetes to Firmicutes: captivity changes the gut microbiota composition and diversity in a social subterranean rodent
title_full_unstemmed Bacteroidetes to Firmicutes: captivity changes the gut microbiota composition and diversity in a social subterranean rodent
title_short Bacteroidetes to Firmicutes: captivity changes the gut microbiota composition and diversity in a social subterranean rodent
title_sort bacteroidetes to firmicutes: captivity changes the gut microbiota composition and diversity in a social subterranean rodent
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912604/
https://www.ncbi.nlm.nih.gov/pubmed/36765400
http://dx.doi.org/10.1186/s42523-023-00231-1
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