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Abnormal signal pathways and tumor heterogeneity in osteosarcoma

BACKGROUND: Osteosarcoma (OS) is the most frequent and aggressive primary malignant sarcoma among adolescents and chemotherapy has not substantially progressed for decades. New insights into OS development and therapeutic strategies are urgently needed. METHODS: We analyzed integrated single-cell tr...

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Detalles Bibliográficos
Autores principales: Sun, Yifeng, Zhang, Chunming, Fang, Qiongxuan, Zhang, Wenqiang, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912612/
https://www.ncbi.nlm.nih.gov/pubmed/36759884
http://dx.doi.org/10.1186/s12967-023-03961-7