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Caspase-11 contributes to site-1 protease cleavage and SREBP1 activation in the inflammatory response of macrophages

Sterol regulatory element-binding proteins (SREBPs) are key transcription factors that control fatty acid and cholesterol metabolism. As the major SREBP isoform in macrophages, SREBP1a is also required for inflammatory and phagocytotic functions. However, it is insufficiently understood how SREBP1a...

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Detalles Bibliográficos
Autores principales:	Cheng, Yinglan, Manabe, Ichiro, Hayakawa, Sumio, Endo, Yusuke, Oishi, Yumiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912839/ https://www.ncbi.nlm.nih.gov/pubmed/36776855 http://dx.doi.org/10.3389/fimmu.2023.1009973

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