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Discovery of potential FGFR3 inhibitors via QSAR, pharmacophore modeling, virtual screening and molecular docking studies against bladder cancer

BACKGROUND: Fibroblast growth factor receptor 3 is known as a favorable aim in vast range of cancers, particularly in bladder cancer treatment. Pharmacophore and QSAR modeling approaches are broadly utilized for developing novel compounds for the determination of inhibitory activity versus the biolo...

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Detalles Bibliográficos
Autores principales:	Ganji, Mahmoud, Bakhshi, Shohreh, Shoari, Alireza, Ahangari Cohan, Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913026/ https://www.ncbi.nlm.nih.gov/pubmed/36765337 http://dx.doi.org/10.1186/s12967-023-03955-5

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