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Doxycycline-Induced Changes in Circulating MMP or TIMP2 Levels Are Not Associated with Skeletal-Related Event-Free or Overall Survival in Patients with Bone Metastases from Breast Cancer

SIMPLE SUMMARY: The current study was a retrospective exploratory study evaluating whether circulating levels of known targets of doxycycline were altered following administration of doxycycline to bone metastatic breast cancer patients as an indicator of its expected on-target efficacy. Although we...

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Detalles Bibliográficos
Autores principales:	Zhao, Huijun, Pond, Gregory, Simos, Demetrios, Wang, Zhou, Robertson, Susan, Singh, Gurmit, Vandermeer, Lisa, Clemons, Mark, Addison, Christina Lynn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913061/ https://www.ncbi.nlm.nih.gov/pubmed/36765529 http://dx.doi.org/10.3390/cancers15030571

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