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Niclosamide Revitalizes Sorafenib through Insulin-like Growth Factor 1 Receptor (IGF-1R)/Stemness and Metabolic Changes in Hepatocellular Carcinoma
SIMPLE SUMMARY: Sorafenib resistance is the major challenge for the unsatisfactory response to targeted therapies in advanced hepatocellular carcinoma (HCC). Combination therapy may overcome the obstacle and is an increasingly acceptable strategy. In this study, we demonstrate that niclosamide can i...
Autores principales: | Peng, Syue-Wei, Ngo, Mai-Huong T., Kuo, Yung-Che, Teng, Ming-Hao, Guo, Chin-Lin, Lai, Hung-Cheng, Chang, Te-Sheng, Huang, Yen-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913083/ https://www.ncbi.nlm.nih.gov/pubmed/36765890 http://dx.doi.org/10.3390/cancers15030931 |
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