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Implementing HRD Testing in Routine Clinical Practice on Patients with Primary High-Grade Advanced Ovarian Cancer

SIMPLE SUMMARY: Testing for a homologous recombination deficiency (HRD) in primary high-grade ovarian cancer is crucial for recommending the appropriate therapy. Patients with a BRCA germline mutation are defined as harboring an HRD deficiency. However, there is a group of approximately 20% of patie...

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Detalles Bibliográficos
Autores principales: Heitz, Florian, Ataseven, Beyhan, Staniczok, Claudia, Denkert, Carsten, Rhiem, Kerstin, Hahnen, Eric, Heikaus, Sebastian, Moubarak, Malak, Welz, Julia, Dagres, Timoleon, Vrentas, Vasilios, Bommert, Mareike, Schneider, Stephanie, Concin, Nicole, Harter, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913091/
https://www.ncbi.nlm.nih.gov/pubmed/36765776
http://dx.doi.org/10.3390/cancers15030818