Antigene MYCN Silencing by BGA002 Inhibits SCLC Progression Blocking mTOR Pathway and Overcomes Multidrug Resistance

SIMPLE SUMMARY: Small-cell lung cancer (SCLC) is the most aggressive form of lung cancer, is mostly associated with smoking and has a low survival rate. Among the different alterations in genes identified in SCLC, those related to the MYC family have emerged as highly relevant, alterations MYCN part...

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Detalles Bibliográficos
Autores principales: Bortolotti, Sonia, Angelucci, Silvia, Montemurro, Luca, Bartolucci, Damiano, Raieli, Salvatore, Lampis, Silvia, Amadesi, Camilla, Scardovi, Annalisa, Nieddu, Giammario, Cerisoli, Lucia, Paganelli, Francesca, Chiarini, Francesca, Teti, Gabriella, Falconi, Mirella, Pession, Andrea, Hrelia, Patrizia, Tonelli, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913109/
https://www.ncbi.nlm.nih.gov/pubmed/36765949
http://dx.doi.org/10.3390/cancers15030990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913109/
https://www.ncbi.nlm.nih.gov/pubmed/36765949
http://dx.doi.org/10.3390/cancers15030990

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