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Tumor Growth Suppression of Pancreatic Cancer Orthotopic Xenograft Model by CEA-Targeting CAR-T Cells

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma is one of the most lethal malignancies, and there are vast unmet medical needs. In this study, we hypothesized that chimeric antigen receptor engineered T cell (CAR-T) targeting carcinoembryonic antigen (CEA) would be effective in the treatment of pan...

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Detalles Bibliográficos
Autores principales:	Sato, Osamu, Tsuchikawa, Takahiro, Kato, Takuma, Amaishi, Yasunori, Okamoto, Sachiko, Mineno, Junichi, Takeuchi, Yuta, Sasaki, Katsunori, Nakamura, Toru, Umemoto, Kazufumi, Suzuki, Tomohiro, Wang, Linan, Wang, Yizheng, Hatanaka, Kanako C., Mitsuhashi, Tomoko, Hatanaka, Yutaka, Shiku, Hiroshi, Hirano, Satoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913141/ https://www.ncbi.nlm.nih.gov/pubmed/36765558 http://dx.doi.org/10.3390/cancers15030601

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