Prognostic Significance of Integrin Subunit Alpha 2 (ITGA2) and Role of Mechanical Cues in Resistance to Gemcitabine in Pancreatic Ductal Adenocarcinoma (PDAC)

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and chemoresistant cancer, with a poor overall survival. The stiff stroma surrounding PDAC is known to be involved in chemoresistance via mechanical cues, although the mechanisms behind it are poorly understood. Here, we invest...

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Detalles Bibliográficos
Autores principales: Gregori, Alessandro, Bergonzini, Cecilia, Capula, Mjriam, Mantini, Giulia, Khojasteh-Leylakoohi, Fatemeh, Comandatore, Annalisa, Khalili-Tanha, Ghazaleh, Khooei, Alireza, Morelli, Luca, Avan, Amir, Danen, Erik H., Schmidt, Thomas, Giovannetti, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913151/
https://www.ncbi.nlm.nih.gov/pubmed/36765586
http://dx.doi.org/10.3390/cancers15030628

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