Seizures in activating calcium‐sensing receptor antibodies positive autoimmune hypoparathyroidism and preponderance of steroids therapy: A case report

A 55‐year‐old female patient presented with generalized tonic–clonic seizures. Laboratory evaluation revealed low calcium (4.9 mg/dl), low PTH (0.9 pg/ml), and positive activating CaSR antibodies. The condition was diagnosed as autoimmune hypoparathyroidism. Calcium and vitamin D supplements did not...

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Autores principales: Khan, Qaisar Ali, Shahi, Ameena, Shahi, Alishba, Baqi, Abdul, Tango, Tamara, Verma, Ravina, Hamid, Asrah Abdul, Saravanan, Priyadharshini, Alam, Mazhar, Shinwari, Ismail Khan, Ul Ain, Hoor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913179/
https://www.ncbi.nlm.nih.gov/pubmed/36789314
http://dx.doi.org/10.1002/ccr3.6901
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author Khan, Qaisar Ali
Shahi, Ameena
Shahi, Alishba
Baqi, Abdul
Tango, Tamara
Verma, Ravina
Hamid, Asrah Abdul
Saravanan, Priyadharshini
Alam, Mazhar
Shinwari, Ismail Khan
Ul Ain, Hoor
author_facet Khan, Qaisar Ali
Shahi, Ameena
Shahi, Alishba
Baqi, Abdul
Tango, Tamara
Verma, Ravina
Hamid, Asrah Abdul
Saravanan, Priyadharshini
Alam, Mazhar
Shinwari, Ismail Khan
Ul Ain, Hoor
author_sort Khan, Qaisar Ali
collection PubMed
description A 55‐year‐old female patient presented with generalized tonic–clonic seizures. Laboratory evaluation revealed low calcium (4.9 mg/dl), low PTH (0.9 pg/ml), and positive activating CaSR antibodies. The condition was diagnosed as autoimmune hypoparathyroidism. Calcium and vitamin D supplements did not correct the patient's hypocalcemia. The addition of prednisone to vitamin supplements showed a better response and corrected the hypocalcemia. The patient remained in seizure‐free for one year.
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spelling pubmed-99131792023-02-13 Seizures in activating calcium‐sensing receptor antibodies positive autoimmune hypoparathyroidism and preponderance of steroids therapy: A case report Khan, Qaisar Ali Shahi, Ameena Shahi, Alishba Baqi, Abdul Tango, Tamara Verma, Ravina Hamid, Asrah Abdul Saravanan, Priyadharshini Alam, Mazhar Shinwari, Ismail Khan Ul Ain, Hoor Clin Case Rep Case Report A 55‐year‐old female patient presented with generalized tonic–clonic seizures. Laboratory evaluation revealed low calcium (4.9 mg/dl), low PTH (0.9 pg/ml), and positive activating CaSR antibodies. The condition was diagnosed as autoimmune hypoparathyroidism. Calcium and vitamin D supplements did not correct the patient's hypocalcemia. The addition of prednisone to vitamin supplements showed a better response and corrected the hypocalcemia. The patient remained in seizure‐free for one year. John Wiley and Sons Inc. 2023-02-10 /pmc/articles/PMC9913179/ /pubmed/36789314 http://dx.doi.org/10.1002/ccr3.6901 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Khan, Qaisar Ali
Shahi, Ameena
Shahi, Alishba
Baqi, Abdul
Tango, Tamara
Verma, Ravina
Hamid, Asrah Abdul
Saravanan, Priyadharshini
Alam, Mazhar
Shinwari, Ismail Khan
Ul Ain, Hoor
Seizures in activating calcium‐sensing receptor antibodies positive autoimmune hypoparathyroidism and preponderance of steroids therapy: A case report
title Seizures in activating calcium‐sensing receptor antibodies positive autoimmune hypoparathyroidism and preponderance of steroids therapy: A case report
title_full Seizures in activating calcium‐sensing receptor antibodies positive autoimmune hypoparathyroidism and preponderance of steroids therapy: A case report
title_fullStr Seizures in activating calcium‐sensing receptor antibodies positive autoimmune hypoparathyroidism and preponderance of steroids therapy: A case report
title_full_unstemmed Seizures in activating calcium‐sensing receptor antibodies positive autoimmune hypoparathyroidism and preponderance of steroids therapy: A case report
title_short Seizures in activating calcium‐sensing receptor antibodies positive autoimmune hypoparathyroidism and preponderance of steroids therapy: A case report
title_sort seizures in activating calcium‐sensing receptor antibodies positive autoimmune hypoparathyroidism and preponderance of steroids therapy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913179/
https://www.ncbi.nlm.nih.gov/pubmed/36789314
http://dx.doi.org/10.1002/ccr3.6901
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