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Is Reflex Germline BRCA1/2 Testing Necessary in Women Diagnosed with Non-Mucinous High-Grade Epithelial Ovarian Cancer Aged 80 Years or Older?
SIMPLE SUMMARY: Approximately 15% of patients diagnosed with high-grade non-mucinous epithelial ovarian cancer (EOC) have a germline BRCA1/2 mutation, although all patients are often able to access germline testing. Importantly, the risk of familial ovarian cancer reduces with advancing age at diagn...
Autores principales: | Morgan, Robert D., Burghel, George J., Flaum, Nicola, Bulman, Michael, Smith, Philip, Clamp, Andrew R., Hasan, Jurjees, Mitchell, Claire L., Salih, Zena, Woodward, Emma R., Lalloo, Fiona, Crosbie, Emma J., Edmondson, Richard J., Schlecht, Helene, Jayson, Gordon C., Evans, D. Gareth R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913244/ https://www.ncbi.nlm.nih.gov/pubmed/36765687 http://dx.doi.org/10.3390/cancers15030730 |
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