Cargando…
Targeting Class I-II-III PI3Ks in Cancer Therapy: Recent Advances in Tumor Biology and Preclinical Research
SIMPLE SUMMARY: The PI3K/AKT pathway is one of the most important signaling nodes in cancer. While class I PI3K roles in cancer are well known, class II and III functions in physiology and physiopathology are poorly studied. Moreover, the interactions between pathways controlled by all three classes...
Autores principales: | Thibault, Benoît, Ramos-Delgado, Fernanda, Guillermet-Guibert, Julie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913247/ https://www.ncbi.nlm.nih.gov/pubmed/36765741 http://dx.doi.org/10.3390/cancers15030784 |
Ejemplares similares
-
Class I PI3Ks in arterial thrombosis
por: Laurent, Pierre-Alexandre, et al.
Publicado: (2019) -
Heterogeneity of Phosphatidylinositol-3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin Activation in Cancer: Is PI3K Isoform Specificity Important?
por: Cintas, Célia, et al.
Publicado: (2018) -
Signal-Targeted Therapies and Resistance Mechanisms in Pancreatic Cancer: Future Developments Reside in Proteomics
por: Cintas, Célia, et al.
Publicado: (2018) -
Class II PI3Ks at the Intersection between Signal Transduction and Membrane Trafficking
por: Margaria, Jean Piero, et al.
Publicado: (2019) -
Dissection of the Interplay between Class I PI3Ks and Rac Signaling in Phagocytic Functions
por: Costa, Carlotta, et al.
Publicado: (2010)