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Treatment with Anti-HER2 Chimeric Antigen Receptor Tumor-Infiltrating Lymphocytes (CAR-TILs) Is Safe and Associated with Antitumor Efficacy in Mice and Companion Dogs

SIMPLE SUMMARY: CAR-T cells are immune cells equipped with a claw that enable them to bind cancer cells. Usually, CAR-T cells are made using immune cells from blood. Here, we tested the hypothesis that also immune cells that reside in the tumor, so called tumor-infiltrating lymphocytes, can also be...

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Detalles Bibliográficos
Autores principales: Forsberg, Elin M. V., Riise, Rebecca, Saellström, Sara, Karlsson, Joakim, Alsén, Samuel, Bucher, Valentina, Hemminki, Akseli E., Olofsson Bagge, Roger, Ny, Lars, Nilsson, Lisa M., Rönnberg, Henrik, Nilsson, Jonas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913266/
https://www.ncbi.nlm.nih.gov/pubmed/36765608
http://dx.doi.org/10.3390/cancers15030648