Pharmacokinetic Analysis of Omomyc Shows Lasting Structural Integrity and Long Terminal Half-Life in Tumor Tissue

SIMPLE SUMMARY: The maintenance of the structural integrity of therapeutic proteins in the target tissue is crucial to their proper function. In this study, we aimed to assess the in vivo stability of the therapeutic protein Omomyc in blood serum and tumor tissue in a xenograft mouse model of colore...

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Detalles Bibliográficos
Autores principales: Beaulieu, Marie-Eve, Martínez-Martín, Sandra, Kaur, Jastrinjan, Castillo Cano, Virginia, Massó-Vallés, Daniel, Foradada Felip, Laia, López-Estévez, Sergio, Serrano del Pozo, Erika, Thabussot, Hugo, Soucek, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913332/
https://www.ncbi.nlm.nih.gov/pubmed/36765784
http://dx.doi.org/10.3390/cancers15030826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913332/
https://www.ncbi.nlm.nih.gov/pubmed/36765784
http://dx.doi.org/10.3390/cancers15030826

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