MAPK Pathway Inhibitors in Thyroid Cancer: Preclinical and Clinical Data

SIMPLE SUMMARY: The Ras-Raf-MEK-ERK signaling pathway is responsible for regulating cell proliferation, differentiation and survival. Overexpression and overactivation of members within the signaling cascade have been observed in many solid cancers and especially in thyroid cancers. These members ar...

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Detalles Bibliográficos
Autores principales: Schubert, Louis, Mariko, Mohamed Lamine, Clerc, Jérôme, Huillard, Olivier, Groussin, Lionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913385/
https://www.ncbi.nlm.nih.gov/pubmed/36765665
http://dx.doi.org/10.3390/cancers15030710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913385/
https://www.ncbi.nlm.nih.gov/pubmed/36765665
http://dx.doi.org/10.3390/cancers15030710

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