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Current Landscape and Potential Challenges of Immune Checkpoint Inhibitors in Microsatellite Stable Metastatic Colorectal Carcinoma

SIMPLE SUMMARY: The implementation of immunotherapy in the therapeutic landscape of colorectal carcinoma has been difficult due to the inefficacy reported in early clinical trials. Nevertheless, a small subset of tumors deficient in DNA mismatch repair proteins show excellent responses to immune che...

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Detalles Bibliográficos
Autores principales: San-Román-Gil, María, Torres-Jiménez, Javier, Pozas, Javier, Esteban-Villarrubia, Jorge, Albarrán-Fernández, Víctor, Álvarez-Ballesteros, Pablo, Chamorro-Pérez, Jesús, Rosero-Rodríguez, Diana, Orejana-Martín, Inmaculada, Martínez-Delfrade, Íñigo, Reguera-Puertas, Pablo, Fuentes-Mateos, Raquel, Ferreiro-Monteagudo, Reyes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913409/
https://www.ncbi.nlm.nih.gov/pubmed/36765821
http://dx.doi.org/10.3390/cancers15030863