Cargando…

Genetics, Genomics and Emerging Molecular Therapies of Pancreatic Cancer

SIMPLE SUMMARY: This review article is a summary of the current state of knowledge regarding the genetics of pancreatic cancer and a presentation of possible treatment options reflecting genomic medicine advances and a personalised medicine approach. Several oncogenes in which somatic changes lead t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Jakub, Mroczek, Magdalena, Mach, Anna, Stępień, Maria, Aplas, Angelika, Pronobis-Szczylik, Bartosz, Bukowski, Szymon, Mielczarek, Magda, Gajewska, Ewelina, Topolski, Piotr, Król, Zbigniew J., Szyda, Joanna, Dobosz, Paula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913594/ https://www.ncbi.nlm.nih.gov/pubmed/36765737 http://dx.doi.org/10.3390/cancers15030779

Ejemplares similares

The cancer-risk variant frequency among Polish population reported by the first national whole-genome sequencing study
por: Mroczek, Magdalena, et al.
Publicado: (2023)

Gene Variants Related to Cardiovascular and Pulmonary Diseases May Correlate with Severe Outcome of COVID-19
por: Sypniewski, Mateusz, et al.
Publicado: (2022)

Beyond GWAS—Could Genetic Differentiation within the Allograft Rejection Pathway Shape Natural Immunity to COVID-19?
por: Szyda, Joanna, et al.
Publicado: (2022)

Better safe than sorry—Whole-genome sequencing indicates that missense variants are significant in susceptibility to COVID-19
por: Słomian, Dawid, et al.
Publicado: (2023)

Identification and annotation of breed-specific single nucleotide polymorphisms in Bos taurus genomes
por: Czech, Bartosz, et al.
Publicado: (2018)

WGS Data Collections: How Do Genomic Databases Transform Medicine?
por: Król, Zbigniew J., et al.
Publicado: (2023)

DNA sequence features underlying large-scale duplications and deletions in human
por: Kołomański, Mateusz, et al.
Publicado: (2022)

The application of deep learning for the classification of correct and incorrect SNP genotypes from whole-genome DNA sequencing pipelines
por: Kotlarz, Krzysztof, et al.
Publicado: (2020)

Identification of functional features underlying heat stress response in Sprague–Dawley rats using mixed linear models
por: Kotlarz, Krzysztof, et al.
Publicado: (2022)

The assessment of inter-individual variation of whole-genome DNA sequence in 32 cows
por: Szyda, Joanna, et al.
Publicado: (2015)

An effect of large-scale deletions and duplications on transcript expression
por: Mielczarek, Magda, et al.
Publicado: (2022)

Genetic Parameters of Workability Traits in the Population of Polish Holstein-Friesian Cows Based on Conventional and Genomic Data
por: Szymik, Bartosz, et al.
Publicado: (2021)

The Thousand Polish Genomes—A Database of Polish Variant Allele Frequencies
por: Kaja, Elżbieta, et al.
Publicado: (2022)

Steviol Glycosides Supplementation Affects Lipid Metabolism in High-Fat Fed STZ-Induced Diabetic Rats
por: Kurek, Jakub Michał, et al.
Publicado: (2020)

Patterns of DNA variation between the autosomes, the X chromosome and the Y chromosome in Bos taurus genome
por: Czech, Bartosz, et al.
Publicado: (2020)

Steviol Glycoside, L-Arginine, and Chromium(III) Supplementation Attenuates Abnormalities in Glucose Metabolism in Streptozotocin-Induced Mildly Diabetic Rats Fed a High-Fat Diet
por: Kurek, Jakub Michał, et al.
Publicado: (2022)

Landscape of copy number variations in Bos taurus: individual – and inter-breed variability
por: Mielczarek, M., et al.
Publicado: (2018)

One-Step Preparation of Highly Stable Copper–Zinc Ferrite Nanoparticles in Water Suitable for MRI Thermometry
por: Lachowicz, Dorota, et al.
Publicado: (2022)

The Spectrum of the Heterozygous Effect in Biallelic Mendelian Diseases—The Symptomatic Heterozygote Issue
por: Kalyta, Kateryna, et al.
Publicado: (2023)

Bioinformatic modelling of SARS-CoV-2 pandemic with a focus on country-specific dynamics
por: Liu, Jakub, et al.
Publicado: (2023)

The Relationship between Dietary, Serum and Hair Levels of Minerals (Fe, Zn, Cu) and Glucose Metabolism Indices in Obese Type 2 Diabetic Patients
por: Król, Ewelina, et al.
Publicado: (2018)

Utilization of information from gene networks towards a better understanding of functional similarities between complex traits: a dairy cattle model
por: Frąszczak, Magdalena, et al.
Publicado: (2015)

Apigenin Modulates AnxA6- and TNAP-Mediated Osteoblast Mineralization
por: Mroczek, Joanna, et al.
Publicado: (2022)

The Composites of PCL and Tetranuclear Titanium(IV)-oxo Complexes as Materials Exhibiting the Photocatalytic and the Antimicrobial Activity
por: Kubiak, Barbara, et al.
Publicado: (2021)

The Role of Selected Adipocytokines in Ovarian Cancer and Endometrial Cancer
por: Stępień, Sebastian, et al.
Publicado: (2023)

Population Structure Analysis of Bull Genomes of European and Western Ancestry
por: Chung, Neo Christopher, et al.
Publicado: (2017)

Fecal microbiota and their association with heat stress in Bos taurus
por: Czech, Bartosz, et al.
Publicado: (2022)

Consumption of Antibiotics and Epidemiology of Clostridioides difficile in the European Union in 2016—Opportunity for Practical Application of Aggregate ECDC Data
por: Jachowicz, Estera, et al.
Publicado: (2020)

Surface Properties and Morphology of Boron Carbide Nanopowders Obtained by Lyophilization of Saccharide Precursors
por: Kozień, Dawid, et al.
Publicado: (2021)

Folic Acid and Protein Content in Maternal Diet and Postnatal High-Fat Feeding Affect the Tissue Levels of Iron, Zinc, and Copper in the Rat
por: Król, Ewelina, et al.
Publicado: (2011)

Supplementary Chromium(III) Propionate Complex Does Not Protect Against Insulin Resistance in High-Fat-Fed Rats
por: Król, Ewelina, et al.
Publicado: (2014)

Developing a novel positronium biomarker for cardiac myxoma imaging
por: Moskal, Paweł, et al.
Publicado: (2023)

The Effects of Supplementary Mulberry Leaf (Morus alba) Extracts on the Trace Element Status (Fe, Zn and Cu) in Relation to Diabetes Management and Antioxidant Indices in Diabetic Rats
por: Król, Ewelina, et al.
Publicado: (2016)

The Therapeutic Aspects of the Endocannabinoid System (ECS) for Cancer and their Development: From Nature to Laboratory
por: Khan, Mohammed I., et al.
Publicado: (2016)

MicroRNAs as Potential Biomarkers in Gynecological Cancers
por: Miśkiewicz, Joanna, et al.
Publicado: (2023)

Polish translation studies in action: concepts, methodologies, applications : a reader
por: Boncza Bukowski, Piotr, et al.
Publicado: (2019)

Effects of Ni/Co doping on structural and electronic properties of 122 and 112 families of Eu based iron pnictides
por: Stępień, Joanna, et al.
Publicado: (2023)

Host transcriptome and microbiome interactions in Holstein cattle under heat stress condition
por: Czech, Bartosz, et al.
Publicado: (2022)

Motor Function of Children with SMA1 and SMA2 Depends on the Neck and Trunk Muscle Strength, Deformation of the Spine, and the Range of Motion in the Limb Joints
por: Stępień, Agnieszka, et al.
Publicado: (2021)

Challenges of the Immunotherapy: Perspectives and Limitations of the Immune Checkpoint Inhibitor Treatment
por: Dobosz, Paula, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_pe7381rbo8oepbaifshmv1l8nr