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A Network of MicroRNAs and mRNAs Involved in Melanosome Maturation and Trafficking Defines the Lower Response of Pigmentable Melanoma Cells to Targeted Therapy

SIMPLE SUMMARY: Selective inhibitors of mutant BRAFV600E (BRAFi) have revolutionized the treatment of metastatic melanoma patients and represent a powerful example of the efficacy of targeted therapy. However, one of the main limitations of BRAFi is that treated cells put in place several adaptive r...

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Detalles Bibliográficos
Autores principales: Vitiello, Marianna, Mercatanti, Alberto, Podda, Maurizio Salvatore, Baldanzi, Caterina, Prantera, Antonella, Sarti, Samanta, Rizzo, Milena, Salvetti, Alessandra, Conte, Federica, Fiscon, Giulia, Paci, Paola, Poliseno, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913661/
https://www.ncbi.nlm.nih.gov/pubmed/36765859
http://dx.doi.org/10.3390/cancers15030894

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