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RIPK1 Regulates Microglial Activation in Lipopolysaccharide-Induced Neuroinflammation and MPTP-Induced Parkinson’s Disease Mouse Models

Increasing evidence suggests a pivotal role of receptor-interacting protein kinase 1 (RIPK1), an initiator of necroptosis, in neuroinflammation. However, the precise role of RIPK1 in microglial activation remains unclear. In the present study, we explored the role of RIPK1 in lipopolysaccharide (LPS...

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Detalles Bibliográficos
Autores principales: Kim, Do-Yeon, Leem, Yea-Hyun, Park, Jin-Sun, Park, Jung-Eun, Park, Jae-Min, Kang, Jihee Lee, Kim, Hee-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913664/
https://www.ncbi.nlm.nih.gov/pubmed/36766759
http://dx.doi.org/10.3390/cells12030417