Novel Non-Cyclooxygenase Inhibitory Derivative of Sulindac Inhibits Breast Cancer Cell Growth In Vitro and Reduces Mammary Tumorigenesis in Rats

SIMPLE SUMMARY: This study describes a new compound, sulindac sulfide amide (SSA), which is a derivative of the nonsteroidal anti-inflammatory drug (NSAID) sulindac. NSAIDs like sulindac are effective at preventing cancer development and progression, but they are associated with dangerous side effec...

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Detalles Bibliográficos
Autores principales: Tinsley, Heather N., Mathew, Bini, Chen, Xi, Maxuitenko, Yulia Y., Li, Nan, Lowe, Whitney M., Whitt, Jason D., Zhang, Wei, Gary, Bernard D., Keeton, Adam B., Grizzle, William E., Grubbs, Clinton J., Reynolds, Robert C., Piazza, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913705/
https://www.ncbi.nlm.nih.gov/pubmed/36765604
http://dx.doi.org/10.3390/cancers15030646

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