Cargando…

FTO Regulated Intramuscular Fat by Targeting APMAP Gene via an m(6)A-YTHDF2-dependent Manner in Rex Rabbits

N6-methyladenosine (m(6)A) regulates fat development in many ways. Low intramuscular fat (IMF) in rabbit meat seriously affects consumption. In order to improve meat quality, we explored the law of IMF deposition. FTO could increase the expression of APMAP and adipocyte differentiation through methy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Gang, Hong, Tingting, Yu, Lin, Ren, Zhanjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913726/ https://www.ncbi.nlm.nih.gov/pubmed/36766716 http://dx.doi.org/10.3390/cells12030369

Ejemplares similares

METTL3 Regulated the Meat Quality of Rex Rabbits by Controlling PCK2 Expression via a YTHDF2–N6-Methyladenosine Axis
por: Luo, Gang, et al.
Publicado: (2022)

FTO-dependent m(6)A regulates muscle fiber remodeling in an NFATC1–YTHDF2 dependent manner
por: Wang, Wengang, et al.
Publicado: (2023)

N6-Methyladenosine Methylome Profiling of Muscle and Adipose Tissues Reveals Methylase–mRNA Metabolic Regulatory Networks in Fat Deposition of Rex Rabbits
por: Luo, Gang, et al.
Publicado: (2022)

APMAP interacts with lysyl oxidase–like proteins, and disruption of Apmap leads to beneficial visceral adipose tissue expansion
por: Pessentheiner, Ariane R., et al.
Publicado: (2017)

The Characterization and Differential Analysis of m(6)A Methylation in Hycole Rabbit Muscle and Adipose Tissue and Prediction of Regulatory Mechanism about Intramuscular Fat
por: Luo, Gang, et al.
Publicado: (2023)

FTO promotes innate immunity by controlling NOD1 expression via m(6)A-YTHDF2 manner in teleost
por: Geng, Shang, et al.
Publicado: (2022)

RNA N6-methyladenosine demethylase FTO promotes pancreatic cancer progression by inducing the autocrine activity of PDGFC in an m(6)A-YTHDF2-dependent manner
por: Tan, Zhen, et al.
Publicado: (2022)

Identification of N6-Methyladenosine-Related Factors and the Prediction of the Regulatory Mechanism of Hair Follicle Development in Rex and Hycole Rabbits
por: Luo, Gang, et al.
Publicado: (2023)

The adipocyte differentiation protein APMAP is an endogenous suppressor of Aβ production in the brain
por: Mosser, Sebastien, et al.
Publicado: (2015)

Decreased ALKBH5, FTO, and YTHDF2 in Peripheral Blood Are as Risk Factors for Rheumatoid Arthritis
por: Luo, Qing, et al.
Publicado: (2020)

YTHDF1 promotes breast cancer progression by facilitating FOXM1 translation in an m6A-dependent manner
por: Chen, Hengyu, et al.
Publicado: (2022)

METTL3 promotes prostatic hyperplasia by regulating PTEN expression in an m(6)A-YTHDF2-dependent manner
por: Li, Jiaren, et al.
Publicado: (2022)

YTHDF1 Facilitates the Progression of Hepatocellular Carcinoma by Promoting FZD5 mRNA Translation in an m6A-Dependent Manner
por: Liu, Xiangxiang, et al.
Publicado: (2020)

ALKBH5 regulates STAT3 activity to affect the proliferation and tumorigenicity of osteosarcoma via an m6A-YTHDF2-dependent manner
por: Yang, Zechuan, et al.
Publicado: (2022)

Tissue Distribution of Porcine FTO and Its Effect on Porcine Intramuscular Preadipocytes Proliferation and Differentiation
por: Chen, Xiaoling, et al.
Publicado: (2016)

FTO promotes tumour proliferation in bladder cancer via the FTO/miR-576/CDK6 axis in an m6A-dependent manner
por: Zhou, Guanwen, et al.
Publicado: (2021)

Fat mass and obesity-associated factor (FTO)-mediated N6-methyladenosine regulates spermatogenesis in an age-dependent manner
por: Wu, Yifei, et al.
Publicado: (2023)

MMP24 Contributes to Neuropathic Pain in an FTO-Dependent Manner in the Spinal Cord Neurons
por: Ma, Longfei, et al.
Publicado: (2021)

Correction: FTO promotes tumour proliferation in bladder cancer via the FTO/miR-576/CDK6 axis in an m6A-dependent manner
por: Zhou, Guanwen, et al.
Publicado: (2021)

YTHDF2 facilitates aggresome formation via UPF1 in an m(6)A-independent manner
por: Hwang, Hyun Jung, et al.
Publicado: (2023)

The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer’s disease
por: Gerber, Hermeto, et al.
Publicado: (2019)

PA2G4 promotes the metastasis of hepatocellular carcinoma by stabilizing FYN mRNA in a YTHDF2-dependent manner
por: Sun, Sheng, et al.
Publicado: (2022)

METTL3 promotes intrahepatic cholangiocarcinoma progression by regulating IFIT2 expression in an m(6)A-YTHDF2-dependent manner
por: Xu, Qiong-Cong, et al.
Publicado: (2022)

YTHDF3 facilitates triple-negative breast cancer progression and metastasis by stabilizing ZEB1 mRNA in an m(6)A-dependent manner
por: Lin, Yuxiang, et al.
Publicado: (2022)

Retraction Notice to: YTHDF1 Facilitates the Progression of Hepatocellular Carcinoma by Promoting FZD5 mRNA Translation in an m6A-Dependent Manner
por: Liu, Xiangxiang, et al.
Publicado: (2022)

The m(6)A reader YTHDF1 attenuates fulminant hepatitis via MFG-E8 translation in an m(6)A dependent manner
por: Ke, Meng-Yun, et al.
Publicado: (2023)

Microbiome of Total Versus Live Bacteria in the Gut of Rex Rabbits
por: Fu, Xiangchao, et al.
Publicado: (2018)

YTHDF1 Negatively Regulates Treponema pallidum-Induced Inflammation in THP-1 Macrophages by Promoting SOCS3 Translation in an m6A-Dependent Manner
por: Li, Zhijia, et al.
Publicado: (2022)

APMAP Promotes Epithelial-Mesenchymal Transition and Metastasis of Cervical Cancer Cells by Activating the Wnt/β-catenin Pathway
por: Zhu, Xiuting, et al.
Publicado: (2021)

The m(6)A Reader YTHDF1 Facilitates the Tumorigenesis and Metastasis of Gastric Cancer via USP14 Translation in an m(6)A-Dependent Manner
por: Chen, Xiao-Yu, et al.
Publicado: (2021)

The m(6)A Reader YTHDF1 Promotes Lung Carcinoma Progression via Regulating Ferritin Mediate Ferroptosis in an m(6)A-Dependent Manner
por: Diao, Hongtao, et al.
Publicado: (2023)

Genomic regions influencing intramuscular fat in divergently selected rabbit lines
por: Sosa‐Madrid, Bolívar S., et al.
Publicado: (2019)

RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A‐YTHDF2‐dependent manner
por: Shen, Dingcheng, et al.
Publicado: (2023)

Overexpression of FTO inhibits excessive proliferation and promotes the apoptosis of human glomerular mesangial cells by alleviating FOXO6 m6A modification via YTHDF3-dependent mechanisms
por: Zhuang, Xingxing, et al.
Publicado: (2023)

The complete mitochondrial DNA sequence of Chuanbai Rex rabbit (Oryctolagus cuniculus)
por: Wang, Xiang, et al.
Publicado: (2021)

LINC00659 cooperated with ALKBH5 to accelerate gastric cancer progression by stabilising JAK1 mRNA in an m(6)A‐YTHDF2‐dependent manner
por: Fang, Yuan, et al.
Publicado: (2023)

RNA demethylase ALKBH5 prevents pancreatic cancer progression by posttranscriptional activation of PER1 in an m6A-YTHDF2-dependent manner
por: Guo, Xingya, et al.
Publicado: (2020)

Methyltransferase-like 3 aggravates endoplasmic reticulum stress in preeclampsia by targeting TMBIM6 in YTHDF2-dependent manner
por: Chen, Yangyang, et al.
Publicado: (2023)

FTO promotes proliferation and migration of bladder cancer via enhancing stability of STAT3 mRNA in an m6A-dependent manner
por: Sun, Zhuang, et al.
Publicado: (2023)

YTHDF1 promotes mRNA degradation via YTHDF1‐AGO2 interaction and phase separation
por: Li, Jiong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qpm969ervt0i02eqp8h7ktnlap