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Important Requirements for Desorption/Ionization Mass Spectrometric Measurements of Temozolomide-Induced 2′-Deoxyguanosine Methylations in DNA

SIMPLE SUMMARY: Monitoring chemical action of drugs directly at their molecular target would be particularly valuable for personalized medicine. In temozolomide-exposed biological samples, 2′-deoxyguanosines and O6-methylated species are compounds of interest to monitor chemical effects. However, th...

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Detalles Bibliográficos
Autores principales:	Fresnais, Margaux, Jung, Ina, Klein, Uli B., Miller, Aubry K., Turcan, Sevin, Haefeli, Walter E., Burhenne, Jürgen, Longuespée, Rémi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913758/ https://www.ncbi.nlm.nih.gov/pubmed/36765673 http://dx.doi.org/10.3390/cancers15030716

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