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Enhanced De Novo Lipid Synthesis Mediated by FASN Induces Chemoresistance in Colorectal Cancer

SIMPLE SUMMARY: Resistance to oxaliplatin threatens the prognosis in of colorectal cancer (CRC). As previous studies have aroused interest in fatty acid metabolism in cancer, we determined whether fatty acid biosynthesis contribute to oxaliplatin resistance in CRC. By leveraging the GEO databases, F...

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Detalles Bibliográficos
Autores principales: Han, Lingyu, Dai, Weixing, Luo, Wenqin, Ye, Li, Fang, Hongsheng, Mo, Shaobo, Li, Qingguo, Xu, Ye, Wang, Renjie, Cai, Guoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913810/
https://www.ncbi.nlm.nih.gov/pubmed/36765520
http://dx.doi.org/10.3390/cancers15030562