Germ Cell Maintenance and Sustained Testosterone and Precursor Hormone Production in Human Prepubertal Testis Organ Culture with Tissues from Boys 7 Years+ under Conditions from Adult Testicular Tissue

Human prepubertal testicular tissues are rare, but organ culture conditions to develop a system for human in vitro-spermatogenesis are an essential option for fertility preservation in prepubertal boys subjected to gonadotoxic therapy. To avoid animal testing in line with the 3Rs principle, organ cu...

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Detalles Bibliográficos
Autores principales: Aden, Neels Lennart, Bleeke, Matthias, Kordes, Uwe R., Brunne, Bianka, Holstermann, Barbara, Biemann, Ronald, Ceglarek, Uta, Soave, Armin, Salzbrunn, Andrea, Schneider, Stefan W., von Kopylow, Kathrein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913959/
https://www.ncbi.nlm.nih.gov/pubmed/36766757
http://dx.doi.org/10.3390/cells12030415

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