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Metformin Therapy and Breast Cancer Incidence in the Ha’il Region
Background: Metformin is a drug used to treat patients with type 2 diabetes, especially those who suffer from obesity. It is also used in the treatment of women with polycystic ovary syndrome (PCOS). This disease is related to insulin resistance and multiplied blood sugar ranges. Furthermore, it has...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914021/ https://www.ncbi.nlm.nih.gov/pubmed/36766896 http://dx.doi.org/10.3390/healthcare11030321 |
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author | Osman, Mhdia Muqbel, Taif Abduallh, Ahad Alanazi, Shuruq Khalifa, Nasrin E. Khojali, Weam M. A. Elagib, Halima Mustafa Hussein, Weiam Abdallah, Marwa H. |
author_facet | Osman, Mhdia Muqbel, Taif Abduallh, Ahad Alanazi, Shuruq Khalifa, Nasrin E. Khojali, Weam M. A. Elagib, Halima Mustafa Hussein, Weiam Abdallah, Marwa H. |
author_sort | Osman, Mhdia |
collection | PubMed |
description | Background: Metformin is a drug used to treat patients with type 2 diabetes, especially those who suffer from obesity. It is also used in the treatment of women with polycystic ovary syndrome (PCOS). This disease is related to insulin resistance and multiplied blood sugar ranges. Furthermore, it has been established that the use of metformin improves the menstrual cycles and ovulation rates of these women. Methods: A structured questionnaire was conducted to determine the prevalence of breast cancer among women using metformin in the Ha’il region. Result: The incidence of breast cancer among women using metformin in the Ha’il region is very low. Thus, it can be said that breast cancer cases declined among diabetics taking metformin. This means that metformin use is associated with a lower risk of breast cancer in women with type 2 diabetes, even in cases where these women have a family history of breast cancer. Conclusions: According to previous findings, metformin has been linked to lower breast cancer risk in women with type 2 diabetes. Furthermore, the findings of this study corroborate the literature on this subject by indicating that there is a substantial connection between metformin use and a lower risk of breast cancer in women with type 2 diabetes. However, further in vitro and in vivo experiments are crucial to investigate the protective effect of metformin against breast cancer and to confirm our findings. |
format | Online Article Text |
id | pubmed-9914021 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99140212023-02-11 Metformin Therapy and Breast Cancer Incidence in the Ha’il Region Osman, Mhdia Muqbel, Taif Abduallh, Ahad Alanazi, Shuruq Khalifa, Nasrin E. Khojali, Weam M. A. Elagib, Halima Mustafa Hussein, Weiam Abdallah, Marwa H. Healthcare (Basel) Article Background: Metformin is a drug used to treat patients with type 2 diabetes, especially those who suffer from obesity. It is also used in the treatment of women with polycystic ovary syndrome (PCOS). This disease is related to insulin resistance and multiplied blood sugar ranges. Furthermore, it has been established that the use of metformin improves the menstrual cycles and ovulation rates of these women. Methods: A structured questionnaire was conducted to determine the prevalence of breast cancer among women using metformin in the Ha’il region. Result: The incidence of breast cancer among women using metformin in the Ha’il region is very low. Thus, it can be said that breast cancer cases declined among diabetics taking metformin. This means that metformin use is associated with a lower risk of breast cancer in women with type 2 diabetes, even in cases where these women have a family history of breast cancer. Conclusions: According to previous findings, metformin has been linked to lower breast cancer risk in women with type 2 diabetes. Furthermore, the findings of this study corroborate the literature on this subject by indicating that there is a substantial connection between metformin use and a lower risk of breast cancer in women with type 2 diabetes. However, further in vitro and in vivo experiments are crucial to investigate the protective effect of metformin against breast cancer and to confirm our findings. MDPI 2023-01-20 /pmc/articles/PMC9914021/ /pubmed/36766896 http://dx.doi.org/10.3390/healthcare11030321 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Osman, Mhdia Muqbel, Taif Abduallh, Ahad Alanazi, Shuruq Khalifa, Nasrin E. Khojali, Weam M. A. Elagib, Halima Mustafa Hussein, Weiam Abdallah, Marwa H. Metformin Therapy and Breast Cancer Incidence in the Ha’il Region |
title | Metformin Therapy and Breast Cancer Incidence in the Ha’il Region |
title_full | Metformin Therapy and Breast Cancer Incidence in the Ha’il Region |
title_fullStr | Metformin Therapy and Breast Cancer Incidence in the Ha’il Region |
title_full_unstemmed | Metformin Therapy and Breast Cancer Incidence in the Ha’il Region |
title_short | Metformin Therapy and Breast Cancer Incidence in the Ha’il Region |
title_sort | metformin therapy and breast cancer incidence in the ha’il region |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914021/ https://www.ncbi.nlm.nih.gov/pubmed/36766896 http://dx.doi.org/10.3390/healthcare11030321 |
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