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Prevalence of HIV and Viral Hepatitis Markers among Healthcare Workers in the Republic of Guinea
Healthcare workers are much more likely to be infected with HIV and hepatitis viruses compared to the general population. Although healthcare workers are more aware of HIV and hepatitis viruses, several countries in Africa lack a comprehensive grasp of disease routes and transmission risks. The aim...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914033/ https://www.ncbi.nlm.nih.gov/pubmed/36766482 http://dx.doi.org/10.3390/diagnostics13030378 |
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author | Ostankova, Yulia V. Shchemelev, Alexander N. Boumbaly, Sanaba Balde, Thierno A. L. Zueva, Elena B. Valutite, Diana E. Serikova, Elena N. Davydenko, Vladimir S. Skvoroda, Vsevolod V. Vasileva, Daria A. Semenov, Alexander V. Esaulenko, Elena V. Totolian, Areg A. |
author_facet | Ostankova, Yulia V. Shchemelev, Alexander N. Boumbaly, Sanaba Balde, Thierno A. L. Zueva, Elena B. Valutite, Diana E. Serikova, Elena N. Davydenko, Vladimir S. Skvoroda, Vsevolod V. Vasileva, Daria A. Semenov, Alexander V. Esaulenko, Elena V. Totolian, Areg A. |
author_sort | Ostankova, Yulia V. |
collection | PubMed |
description | Healthcare workers are much more likely to be infected with HIV and hepatitis viruses compared to the general population. Although healthcare workers are more aware of HIV and hepatitis viruses, several countries in Africa lack a comprehensive grasp of disease routes and transmission risks. The aim of this study was to assess the prevalence of the serological and molecular biological markers of HIV and viral hepatitis among healthcare workers in the Republic of Guinea. The study material was 74 blood serum samples collected from healthcare workers who received additional training at the Institute of Applied Biological Research of Guinea (IRBAG, Kindia, Republic of Guinea). The markers examined included HBsAg, HBeAg, anti-HBs IgG, anti-HBcore IgG, anti-HCV qualitative determination, anti-HEV IgM and IgG, anti-HAV IgM and IgG, and anti-HIV. For viral DNA and RNA detection, nucleic acids were extracted from blood serum, and viral presence was inferred using real-time PCR with hybridization fluorescence detection. A high prevalence of viral hepatitis B markers was shown, and significantly fewer cases of viral hepatitis C and HIV were detected. Almost all examined medical workers had anti-HAV IgG antibodies, but no antibodies to hepatitis E virus. Apparently, the identified markers depend on the general prevalence of certain pathogens in the region and are associated with the traditions and characteristics of the country’s residents. |
format | Online Article Text |
id | pubmed-9914033 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99140332023-02-11 Prevalence of HIV and Viral Hepatitis Markers among Healthcare Workers in the Republic of Guinea Ostankova, Yulia V. Shchemelev, Alexander N. Boumbaly, Sanaba Balde, Thierno A. L. Zueva, Elena B. Valutite, Diana E. Serikova, Elena N. Davydenko, Vladimir S. Skvoroda, Vsevolod V. Vasileva, Daria A. Semenov, Alexander V. Esaulenko, Elena V. Totolian, Areg A. Diagnostics (Basel) Article Healthcare workers are much more likely to be infected with HIV and hepatitis viruses compared to the general population. Although healthcare workers are more aware of HIV and hepatitis viruses, several countries in Africa lack a comprehensive grasp of disease routes and transmission risks. The aim of this study was to assess the prevalence of the serological and molecular biological markers of HIV and viral hepatitis among healthcare workers in the Republic of Guinea. The study material was 74 blood serum samples collected from healthcare workers who received additional training at the Institute of Applied Biological Research of Guinea (IRBAG, Kindia, Republic of Guinea). The markers examined included HBsAg, HBeAg, anti-HBs IgG, anti-HBcore IgG, anti-HCV qualitative determination, anti-HEV IgM and IgG, anti-HAV IgM and IgG, and anti-HIV. For viral DNA and RNA detection, nucleic acids were extracted from blood serum, and viral presence was inferred using real-time PCR with hybridization fluorescence detection. A high prevalence of viral hepatitis B markers was shown, and significantly fewer cases of viral hepatitis C and HIV were detected. Almost all examined medical workers had anti-HAV IgG antibodies, but no antibodies to hepatitis E virus. Apparently, the identified markers depend on the general prevalence of certain pathogens in the region and are associated with the traditions and characteristics of the country’s residents. MDPI 2023-01-19 /pmc/articles/PMC9914033/ /pubmed/36766482 http://dx.doi.org/10.3390/diagnostics13030378 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ostankova, Yulia V. Shchemelev, Alexander N. Boumbaly, Sanaba Balde, Thierno A. L. Zueva, Elena B. Valutite, Diana E. Serikova, Elena N. Davydenko, Vladimir S. Skvoroda, Vsevolod V. Vasileva, Daria A. Semenov, Alexander V. Esaulenko, Elena V. Totolian, Areg A. Prevalence of HIV and Viral Hepatitis Markers among Healthcare Workers in the Republic of Guinea |
title | Prevalence of HIV and Viral Hepatitis Markers among Healthcare Workers in the Republic of Guinea |
title_full | Prevalence of HIV and Viral Hepatitis Markers among Healthcare Workers in the Republic of Guinea |
title_fullStr | Prevalence of HIV and Viral Hepatitis Markers among Healthcare Workers in the Republic of Guinea |
title_full_unstemmed | Prevalence of HIV and Viral Hepatitis Markers among Healthcare Workers in the Republic of Guinea |
title_short | Prevalence of HIV and Viral Hepatitis Markers among Healthcare Workers in the Republic of Guinea |
title_sort | prevalence of hiv and viral hepatitis markers among healthcare workers in the republic of guinea |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914033/ https://www.ncbi.nlm.nih.gov/pubmed/36766482 http://dx.doi.org/10.3390/diagnostics13030378 |
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