Cargando…

Epidemiological Characteristics of Helicobacter pylori Infection in Children in Northeast Romania

(1) Background: Although gastritis has been associated with multiple etiologies, in pediatrics the main etiology is idiopathic. Many studies have reported mild-to-severe gastritis Helicobacter pylori (H. pylori) as an etiological factor. We evaluated the distribution of the infection with H. pylori...

Descripción completa

Detalles Bibliográficos
Autores principales: Lupu, Ancuta, Miron, Ingrith Crenguta, Cernomaz, Andrei Tudor, Gavrilovici, Cristina, Lupu, Vasile Valeriu, Starcea, Iuliana Magdalena, Cianga, Anca Lavinia, Stana, Bogdan, Tarca, Elena, Fotea, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914034/
https://www.ncbi.nlm.nih.gov/pubmed/36766513
http://dx.doi.org/10.3390/diagnostics13030408
_version_ 1784885570243133440
author Lupu, Ancuta
Miron, Ingrith Crenguta
Cernomaz, Andrei Tudor
Gavrilovici, Cristina
Lupu, Vasile Valeriu
Starcea, Iuliana Magdalena
Cianga, Anca Lavinia
Stana, Bogdan
Tarca, Elena
Fotea, Silvia
author_facet Lupu, Ancuta
Miron, Ingrith Crenguta
Cernomaz, Andrei Tudor
Gavrilovici, Cristina
Lupu, Vasile Valeriu
Starcea, Iuliana Magdalena
Cianga, Anca Lavinia
Stana, Bogdan
Tarca, Elena
Fotea, Silvia
author_sort Lupu, Ancuta
collection PubMed
description (1) Background: Although gastritis has been associated with multiple etiologies, in pediatrics the main etiology is idiopathic. Many studies have reported mild-to-severe gastritis Helicobacter pylori (H. pylori) as an etiological factor. We evaluated the distribution of the infection with H. pylori by age, gender and place of living; (2) Methods: A retrospective study was conducted over a period of 3 years, over a cohort of 1757 patients of both sexes, aged between 1 and 18 years, admitted to a regional gastroenterology center in Iasi, Romania, with clinical signs of gastritis which underwent upper gastrointestinal endoscopy. The research was based on the analysis of data from patient observation charts and hospital discharge tickets, as well as endoscopy result registers; (3) Results: Out of the 1757 children, in 30.8% of cases the H. pylori infection was present. Out of them, 26.8% were males and 73.2% females. The average age of children with an H. pylori infection was higher (14.1 + 2.8 DS), compared with children without H. pylori (12.8 + 3.7 SD), an average difference of 1.3 years (95% confidence interval 0.96 to 1.66; p < 0.001). By place of living, children with H. pylori infection were from urban areas at 24.7% and from rural areas at 75.3%; (4) Conclusions: H. pylori infection incidence is still high in children, especially in teenagers, so extensive prevention and treatment programs are needed.
format Online
Article
Text
id pubmed-9914034
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-99140342023-02-11 Epidemiological Characteristics of Helicobacter pylori Infection in Children in Northeast Romania Lupu, Ancuta Miron, Ingrith Crenguta Cernomaz, Andrei Tudor Gavrilovici, Cristina Lupu, Vasile Valeriu Starcea, Iuliana Magdalena Cianga, Anca Lavinia Stana, Bogdan Tarca, Elena Fotea, Silvia Diagnostics (Basel) Article (1) Background: Although gastritis has been associated with multiple etiologies, in pediatrics the main etiology is idiopathic. Many studies have reported mild-to-severe gastritis Helicobacter pylori (H. pylori) as an etiological factor. We evaluated the distribution of the infection with H. pylori by age, gender and place of living; (2) Methods: A retrospective study was conducted over a period of 3 years, over a cohort of 1757 patients of both sexes, aged between 1 and 18 years, admitted to a regional gastroenterology center in Iasi, Romania, with clinical signs of gastritis which underwent upper gastrointestinal endoscopy. The research was based on the analysis of data from patient observation charts and hospital discharge tickets, as well as endoscopy result registers; (3) Results: Out of the 1757 children, in 30.8% of cases the H. pylori infection was present. Out of them, 26.8% were males and 73.2% females. The average age of children with an H. pylori infection was higher (14.1 + 2.8 DS), compared with children without H. pylori (12.8 + 3.7 SD), an average difference of 1.3 years (95% confidence interval 0.96 to 1.66; p < 0.001). By place of living, children with H. pylori infection were from urban areas at 24.7% and from rural areas at 75.3%; (4) Conclusions: H. pylori infection incidence is still high in children, especially in teenagers, so extensive prevention and treatment programs are needed. MDPI 2023-01-23 /pmc/articles/PMC9914034/ /pubmed/36766513 http://dx.doi.org/10.3390/diagnostics13030408 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lupu, Ancuta
Miron, Ingrith Crenguta
Cernomaz, Andrei Tudor
Gavrilovici, Cristina
Lupu, Vasile Valeriu
Starcea, Iuliana Magdalena
Cianga, Anca Lavinia
Stana, Bogdan
Tarca, Elena
Fotea, Silvia
Epidemiological Characteristics of Helicobacter pylori Infection in Children in Northeast Romania
title Epidemiological Characteristics of Helicobacter pylori Infection in Children in Northeast Romania
title_full Epidemiological Characteristics of Helicobacter pylori Infection in Children in Northeast Romania
title_fullStr Epidemiological Characteristics of Helicobacter pylori Infection in Children in Northeast Romania
title_full_unstemmed Epidemiological Characteristics of Helicobacter pylori Infection in Children in Northeast Romania
title_short Epidemiological Characteristics of Helicobacter pylori Infection in Children in Northeast Romania
title_sort epidemiological characteristics of helicobacter pylori infection in children in northeast romania
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914034/
https://www.ncbi.nlm.nih.gov/pubmed/36766513
http://dx.doi.org/10.3390/diagnostics13030408
work_keys_str_mv AT lupuancuta epidemiologicalcharacteristicsofhelicobacterpyloriinfectioninchildreninnortheastromania
AT mironingrithcrenguta epidemiologicalcharacteristicsofhelicobacterpyloriinfectioninchildreninnortheastromania
AT cernomazandreitudor epidemiologicalcharacteristicsofhelicobacterpyloriinfectioninchildreninnortheastromania
AT gavrilovicicristina epidemiologicalcharacteristicsofhelicobacterpyloriinfectioninchildreninnortheastromania
AT lupuvasilevaleriu epidemiologicalcharacteristicsofhelicobacterpyloriinfectioninchildreninnortheastromania
AT starceaiulianamagdalena epidemiologicalcharacteristicsofhelicobacterpyloriinfectioninchildreninnortheastromania
AT ciangaancalavinia epidemiologicalcharacteristicsofhelicobacterpyloriinfectioninchildreninnortheastromania
AT stanabogdan epidemiologicalcharacteristicsofhelicobacterpyloriinfectioninchildreninnortheastromania
AT tarcaelena epidemiologicalcharacteristicsofhelicobacterpyloriinfectioninchildreninnortheastromania
AT foteasilvia epidemiologicalcharacteristicsofhelicobacterpyloriinfectioninchildreninnortheastromania