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Endothelial Specific Deletion of Autotaxin Improves Stroke Outcomes

Autotaxin (ATX) is an extracellular secretory enzyme (lysophospholipase D) that catalyzes the hydrolysis of lysophosphatidyl choline to lysophosphatidic acid (LPA). The ATX–LPA axis is a well-known pathological mediator of liver fibrosis, metastasis in cancer, pulmonary fibrosis, atherosclerosis, an...

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Detalles Bibliográficos
Autores principales: Bhattarai, Susmita, Subedi, Utsab, Manikandan, Shrivats, Sharma, Sudha, Sharma, Papori, Miller, Chloe, Bhuiyan, Md Shenuarin, Kidambi, Srivatsan, Aidinis, Vassilis, Sun, Hong, Miriyala, Sumitra, Panchatcharam, Manikandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914107/
https://www.ncbi.nlm.nih.gov/pubmed/36766854
http://dx.doi.org/10.3390/cells12030511