A Review on Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of Pancreatic Lesions

The morbidity associated with pancreatectomies limits surgical options for high-risk patients with pancreatic neoplasms that warrant resection. Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) offers a minimally invasive and potentially definitive means to treat pancreatic neuroendocri...

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Autores principales: Karaisz, Fred G., Elkelany, Osama O., Davies, Benjamin, Lozanski, Gerard, Krishna, Somashekar G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914142/
https://www.ncbi.nlm.nih.gov/pubmed/36766643
http://dx.doi.org/10.3390/diagnostics13030536
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author Karaisz, Fred G.
Elkelany, Osama O.
Davies, Benjamin
Lozanski, Gerard
Krishna, Somashekar G.
author_facet Karaisz, Fred G.
Elkelany, Osama O.
Davies, Benjamin
Lozanski, Gerard
Krishna, Somashekar G.
author_sort Karaisz, Fred G.
collection PubMed
description The morbidity associated with pancreatectomies limits surgical options for high-risk patients with pancreatic neoplasms that warrant resection. Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) offers a minimally invasive and potentially definitive means to treat pancreatic neuroendocrine tumors and precancerous pancreatic cystic lesions. In addition, EUS-RFA may play a role in the treatment and palliation of non-surgical cases of pancreatic adenocarcinoma. The efficacy of RFA appears to be further enhanced by systemic immunomodulatory effects. Here, we review current studies on the developing role of EUS-RFA in these pancreatic pathologies.
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spelling pubmed-99141422023-02-11 A Review on Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of Pancreatic Lesions Karaisz, Fred G. Elkelany, Osama O. Davies, Benjamin Lozanski, Gerard Krishna, Somashekar G. Diagnostics (Basel) Review The morbidity associated with pancreatectomies limits surgical options for high-risk patients with pancreatic neoplasms that warrant resection. Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) offers a minimally invasive and potentially definitive means to treat pancreatic neuroendocrine tumors and precancerous pancreatic cystic lesions. In addition, EUS-RFA may play a role in the treatment and palliation of non-surgical cases of pancreatic adenocarcinoma. The efficacy of RFA appears to be further enhanced by systemic immunomodulatory effects. Here, we review current studies on the developing role of EUS-RFA in these pancreatic pathologies. MDPI 2023-02-01 /pmc/articles/PMC9914142/ /pubmed/36766643 http://dx.doi.org/10.3390/diagnostics13030536 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Karaisz, Fred G.
Elkelany, Osama O.
Davies, Benjamin
Lozanski, Gerard
Krishna, Somashekar G.
A Review on Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of Pancreatic Lesions
title A Review on Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of Pancreatic Lesions
title_full A Review on Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of Pancreatic Lesions
title_fullStr A Review on Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of Pancreatic Lesions
title_full_unstemmed A Review on Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of Pancreatic Lesions
title_short A Review on Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of Pancreatic Lesions
title_sort review on endoscopic ultrasound-guided radiofrequency ablation (eus-rfa) of pancreatic lesions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914142/
https://www.ncbi.nlm.nih.gov/pubmed/36766643
http://dx.doi.org/10.3390/diagnostics13030536
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