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The Role of TP53 in Adaptation and Evolution

The TP53 gene is a major player in cancer formation, and it is considered the most important tumor suppressor gene. The p53 protein acts as a transcription factor, and it is involved in DNA repair, senescence, cell-cycle control, autophagy, and apoptosis. Beyond cancer, there is evidence that TP53 i...

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Detalles Bibliográficos
Autores principales: Voskarides, Konstantinos, Giannopoulou, Nefeli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9914165/
https://www.ncbi.nlm.nih.gov/pubmed/36766853
http://dx.doi.org/10.3390/cells12030512